Drug Screening: Are We Doing What We Should?

Neonatal pressure support ventilation: are we doing what we think we are doing?

Assisted modes of mechanical ventilation, including synchronous intermittent mandatory ventilation, pressure support ventilation (PSV), continuous mandatory ventilation, neurally adjusted ventilatory assist, and volume guarantee ventilation, are widely used in neonates, infants, and small children to achieve improved short-term and long-term outcomes.1-3 Specifically, evidence is accumulating t...

What are we doing? Where are we going?

IgA deficiency: what we should-or should not-be doing.

Although IgA deficiency (IgAD) is currently recognised as the most frequent immunodeficiency in humans, individuals with IgAD are largely considered to be healthy and when discovered are usually not investigated further or followed up. The rare occasion when IgAD is a cause for concern is when these individuals require blood or blood products, in which case current practice advises that product...

What Are We Doing When We Assess Programming?

Considerable research has been devoted in recent decades to identifying optimal pedagogical strategies for teaching computer programming. Often the result of these efforts has been to conclude that we have made little progress, as our students consistently perform poorly on the assessments we apply to measure teaching efficacy. In this paper, we suggest that a significant contributor to this po...

Why don't we know more about what we are doing?

There have been huge changes in science and technology in the past 30 years. We now understand the genetic basis of many diseases, and with the complete mapping of the genome, our knowledge will expand tremendously. We have CT, MRI, computer-guided surgery, gait analysis, and a host of other advances which have made medical care for our patients more effective. While these changes have profound...